Aims: Currently, Master seminar course in many disciplines of basic medical sciences are held to taste and there is no attention to the authentic methods of utilization of the resources and student empowerment. The aim of this study was to offer a practical method for holding the seminar course for the graduate students.

Methods: In a descriptive cross-sectional study which was performed during the years 2009-11, all available students of microbial toxins and microbiology disciplines were entered into this study. For the seminar course, 5 sessions of 2-hour were conducted. Evaluating the scientific level and pretest were conducted at the first meeting. For next meetings, the compiled program was given to the students. The interval session was determined 20 to 30 days. Finally, the post-test was taken out. Data were analyzed, using SPSS 12 software with pairwise comparison of the axes through Wilcoxon test.

Results: A table was designed to evaluate skill acquiring and to measure student’s activity at the seminar course. Scientific survey, determining the kind of the produced science, self-sufficiency, competition, applicability, having innovation, relying on the domestic resources, the funds development and making indigenous knowledge could be evaluated. The difference of the pretest and post-test scores were significant in all domains (p<0.05).

Conclusion: Presentation of seminar course with continuing training and assessment method can strengthen the principles and standards of research among the students.