fa مقایسه اثربخشی روش تحریک الکتریکی مغز با جریان مستقیم [tDCS] و پروتکل توانبخشی شناختی کوتاه‌مدت بر بهبود عملکرد حافظه بیماران مبتلا به آلزایمر خفیف پ‍ژوهش در آموزش علوم پزشکی Research in Medical Science Education پژوهشی اصيل Original Research <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;">مقدمه</span></span></span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;">: هدف پژوهش حاضر مقایسه اثربخشی روش </span></span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="color:black"><span style="background-color:#ffffff;">tDCS</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;"> و پروتکل توانبخشی شناختی کوتاه&shy;مدت بر بهبود عملکرد حافظه بیماران مبتلا به آلزایمر خفیف بود. </span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;">روش:</span></span></span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;"> روش پژوهش</span><span style="background:yellow"><span style="background-color:#ffffff;"> شبه &shy;آزمایشی پیش &shy;آزمون و پس &shy;آزمون و پیگیری با دو گروه آزمایش و یک گروه کنترل</span></span><span style="background-color:#ffffff;"> انجام شد. </span><span style="layout-grid-mode:line"><span style="background-color:#ffffff;">جامعه آماری </span><span style="background:yellow"><span style="background-color:#ffffff;">افراد بالای 65 سال که با تشخیص آلزایمر خفیف&nbsp; در سال 1401 در شهر اردبیل به پزشک مغز و اعصاب به صورت سرپایی</span></span><span style="background-color:#ffffff;"> مراجعه کرده&shy; بودند که از بین این افراد،60 نفر به صورت نمونه&shy;گیری دردسترس انتخاب و به صورت تصادفی در دو گروه آزمایش و یک گروه کنترل گمارده شدند.</span></span><span style="background-color:#ffffff;"> سپس روش </span></span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="color:black"><span style="background-color:#ffffff;">tDCS</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;"> به مدت 10 جلسه 20دقیقه &shy;ای روی یک گروه آزمایش و برنامه توانبخشی شناختی کوتاه &shy;مدت به تعداد 9 جلسه&shy; 90 دقیقه&shy;ای بر روی گروه آزمایش دوم اعمال شد و </span><span style="background:yellow"><span style="background-color:#ffffff;">بر روی گروه کنترل مداخله&shy;ای انجام</span></span><span style="background-color:#ffffff;"> نشد. پس&shy;آزمون با فاصله یک هفته اجرا شد و </span><span style="background:yellow"><span style="background-color:#ffffff;">پیگیری یک ماه بعد از پس&shy;آزمون از هر سه گروه به عمل آمد.</span></span><span style="background-color:#ffffff;"> جهت جمع &shy;آوری اطلاعات از آزمون شناختی آدن بروک نسخه تجدید نظر شده استفاده شد. </span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;">نتایج:</span></span></span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;"> نتایج نشان داد که روش </span></span></span></span><span dir="LTR" style="color:black"><span style="background-color:#ffffff;">tDCS</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="background-color:#ffffff;"> تاثیر معنی‌داری بر حافظه پیش&shy;گستر دارد </span><span style="background:yellow"><span style="background-color:#ffffff;">(05/0</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="background:yellow"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">></span></span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="background:yellow"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">p</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="background:yellow"><span b="" nazanin="" style="font-family:"><span style="background-color:#ffffff;">).</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="background-color:#ffffff;"> در مورد متغیر حافظه پس&shy;گستر، اگر چه روش توانبخشی شناختی کوتاه&shy;مدت در پس&shy;آزمون تاثیر معنی&shy;داری نداشته است ولی در بلندمدت تأثیر معنی‌دار داشته است </span><span style="background:yellow"><span style="background-color:#ffffff;">(05/0</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="background:yellow"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">></span></span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="background:yellow"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">p</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="background:yellow"><span b="" nazanin="" style="font-family:"><span style="background-color:#ffffff;">).</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="background-color:#ffffff;"> در مجموع می&shy;توان گفت روش&shy;های به کار گرفته شده در بهبود حافظه بیماران مبتلا به آلزایمر تأثیر معناداری داشته&shy;اند. </span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;">نتیجه&shy; گیری:</span></span></span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="color:black"><span style="background-color:#ffffff;"> از این رو می&shy; توان نتیجه گرفت که از هر دو روش می&shy;توان در جهت بهبود حافظه بیماران مبتلا به آلزایمر خفیف بهره جست.</span></span></span></span></span></span></span></span></span><br> <span style="background-color:#ffffff;">&nbsp;</span> <span style="font-size:11pt"><span style="line-height:107%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">Introduction:</span></span></span></span></b><span lang="EN" style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;"> The purpose of this study was to compare the effectiveness of tDCS method and short-term cognitive rehabilitation protocol on improving memory performance in patients with mild Alzheimer&#39;s disease.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:107%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">Method: </span></span></span></span></b><span lang="EN" style="font-size:12.0pt"><span style="background:yellow"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">The research method was</span></span></span></span></span><span lang="EN" style="font-size:12.0pt"><span style="background:yellow"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;"> a quasi-experimental research method of pre-test, post-test and follow-up was conducted with two experimental groups and one control group. The statistical population of people over 65 years of age who had been diagnosed with mild Alzheimer&#39;s disease in Ardabil city in 2022 and referred to a neurologist on an outpatient basis, from among these people, 60 people were selected by available sampling and randomly in two an experimental group and a control group were assigned. Then, the tDCS method was applied for 10 sessions of 20 minutes on one experimental group and a short-term cognitive rehabilitation program of 9 sessions of 90 minutes was applied on the second experimental group and no intervention was performed on the control group. The post-test was performed with an interval of one week, and the follow-up was done one month after the post-test of all three groups. Aden Brook&#39;s revised version of cognitive test was used to collect data.</span></span></span></span></span><span style="font-size:12.0pt"><span style="line-height:107%"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:107%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">Results:</span></span></span></span></b><span lang="EN" style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;"> The results showed that the tDCS method has a significant effect on long-term memory </span></span></span></span><span style="font-size:12.0pt"><span style="background:yellow"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">(p<0/05)</span></span></span></span></span><span lang="EN" style="font-size:12.0pt"><span style="background:yellow"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">.</span></span></span></span></span><span lang="EN" style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;"> Regarding the post extended memory variable, although the short-term cognitive rehabilitation method did not have a significant effect on the post-test, it did have a significant effect on the long-term </span></span></span></span><span style="font-size:12.0pt"><span style="background:yellow"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">(p<0/05)</span></span></span></span></span><span lang="EN" style="font-size:12.0pt"><span style="background:yellow"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">.</span></span></span></span></span><span lang="EN" style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;"> In general, it can be said that the methods used in improving the memory of Alzheimer&#39;s patients have had a significant effect. </span></span></span></span><span lang="EN" style="font-size:12.0pt"><span style="line-height:107%"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;">Conclusion:</span></span></span></b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="background-color:#ffffff;"> Therefore, it can be concluded that both methods can be used to improve the memory of patients with mild Alzheimer&#39;s. </span></span></span></span></span></span><br> <span style="background-color:#ffffff;">&nbsp;</span> تحریک الکتریکی مغز باجریان مستقیم, توانبخشی شناختی, حافظه, آلزایمر transcranial direct current stimulation, cognitive rehabilitation, memory, Alzheimer's 67 78 http://edcbmj.ir/browse.php?a_code=A-10-3395-1&slc_lang=fa&sid=1 Arezoo Mojarrad آرزو مجرد arezoomojarrad@yahoo.com 100319475328460042427 100319475328460042427 No Esmaeil Sadri Damirchi اسماعیل صدری دمیرچی araz_sadri@yahoo.com 100319475328460042428 100319475328460042428 Yes Ali Sheykholslamy علی شیخ الاسلامی a_sheykholslamy@yahoo.com 100319475328460042429 100319475328460042429 No Ali Rezaii Sharif علی رضایی شریف rezaeisharif@uma.com 100319475328460042430 100319475328460042430 No Vahid Abbasi وحید عباسی v.abbasineuro@gmail.com 100319475328460042431 100319475328460042431 No