Aims: Studying the medical students’ attitudes to their academic major is significant in the improvement of the national planning and evaluation of the curriculum. This study was an attempt to investigate the students’ attitudes toward the traditional and integrated basic sciences curriculum.

Methods: This descriptive-cross sectional study was conducted in 2010 in all of Tehran and Shahid-Beheshti Universities of Medical Sciences and 200 internship medical students were selected using simple random sampling. The students selected from Tehran University of Medical Sciences were assigned to the traditional curriculum and students of Shahid-Beheshti University of Medical Sciences were assigned to the integrated curriculum. Data collection tool was standardized self-administered questionnaire to examine the medical students’ attitude. Statistical analysis of data was done using SPSS 17 software as well as independent T-test to compare the 9 items of the questionnaire in two mentioned universities.

Results: For both of Tehran and Shahid-Beheshti Universities of Medical Sciences, no significant difference was observed between the students’ attitude regarding the items 1, 3, 4, 5, 7 and 9 (p>0.05). However, concerning items 2, 6 and 8, there was a significant difference. Moreover, for items 6 and 8, between the boy students and for item 1, between the girl students of two universities significant difference was observed.

Conclusion: In spite of the lack of positive attitude toward the real importance of the basic sciences, medical students are more interested in the integrated teaching of basic sciences.